Hydrochloric Acid → HCID 68909232, 화합물

HRID 459536노트

반응식

HRID 459536 반응식
Cl.C(O)C.C(OC([NH:12][C@H:13]1[CH2:18][C@H:17]([C:19]([OH:22])([CH3:21])[CH3:20])[CH2:16][CH2:15][C@H:14]1[NH:23][C:24]([C:26]1[NH:27][C:28]2[C:33]([CH:34]=1)=[CH:32][C:31]([Cl:35])=[CH:30][CH:29]=2)=[O:25])=O)(C)(C)C>O1CCOCC1>[ClH:35].[Cl:35][C:31]1[CH:32]=[C:33]2[C:28](=[CH:29][CH:30]=1)[NH:27][C:26]([C:24]([NH:23][C@@H:14]1[CH2:15][CH2:16][C@@H:17]([C:19]([OH:22])([CH3:21])[CH3:20])[CH2:18][C@@H:13]1[NH2:12])=[O:25])=[CH:34]2

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 68907678HCID 68907678, 화합물

생성물 1

HCID 68909232HCID 68909232, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

A 4N hydrogen chloride solution in dioxane (10 ml) was added to an ethanol solution (5 ml) of (1R*,2S*,4R*)-N2tert-butoxycarbonyl-N1-[(5-Chloroindol-2-yl)carbonyl]-4-(1-hydroxy-1-methylethyl)-1,2-cyclohexanediamine, and the mixture was stirred at room temperature for 12 hours. The solvent was distilled off under reduced pressure to obtain the title compound (100 mg) as a colorless oil.

후처리

  1. distillationThe solvent was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-9312e3c5964745b58b9eadfa0e899276
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07192968B2

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