2-Bromo-1-methyl-1H-imidazole → 4-Methoxy-2-(1-methylimidazol-2-yl)benzo(b)furan

HRID 460611

반응식

HRID 460611 반응식
[CH3:1][O:2][C:3]1[C:11]2[CH:10]=[C:9]([Sn](C)(C)C)[O:8][C:7]=2[CH:6]=[CH:5][CH:4]=1.Br[C:17]1[N:18]([CH3:22])[CH:19]=[CH:20][N:21]=1>>[CH3:1][O:2][C:3]1[C:11]2[CH:10]=[C:9]([C:17]3[N:18]([CH3:22])[CH:19]=[CH:20][N:21]=3)[O:8][C:7]=2[CH:6]=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 27732622-Bromo-1-methyl-1H-imidazoleHCID 227291264-Methoxy-2-(trimethylstannyl)benzo(b)furan

생성물 1

HCID 227291464-Methoxy-2-(1-methylimidazol-2-yl)benzo(b)furan수율 53.4%

실험 절차

By the reactions in the same manner as in Starting Material Synthesis Example 87 using 4-methoxy-2-(trimethylstannyl)benzo(b)furan (5.26 g), 2-bromo-1-methylimidazole (2.72 g) and bistriphenylphosphinepalladium dichloride (593 mg), the title compound (2.06 g) was obtained as a yellow oil.

출처 및 근거

ORD 기록
ord-c0ae3ad54bfe48909422715b0dadf4a9
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07196199B2

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