Triphenylphosphine → (2,5-Dimethyl-3-thenyl)triphenylphosphonium chloride

HRID 460953

반응식

HRID 460953 반응식
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20][C:21]1[S:22][C:23]([CH3:28])=[CH:24][C:25]=1[CH2:26][Cl:27]>C1(C)C=CC=CC=1>[Cl-:27].[CH3:20][C:21]1[S:22][C:23]([CH3:28])=[CH:24][C:25]=1[CH2:26][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 128752613-(Chloromethyl)-2,5-dimethylthiophene

생성물 1

HCID 20285688(2,5-Dimethyl-3-thenyl)triphenylphosphonium chloride

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Triphenylphosphine (11.8 g.) and 7.0 g. of 2,5-dimethyl-3-chloromethylthiophene were dissolved in 100 ml. of toluene. The mixture was refluxed overnight under argon, cooled to room temperature and the precipitated white phosphonium salt was collected by filtration, washed several times with cold benzene and dried at 80° C. under high vacuum. The resulting (2,5-dimethyl-3-thenyl)-triphenylphosphonium chloride has a m.p. 246°-250° C.

후처리

  1. temperatureThe mixture was refluxed overnight under argon
  2. filtrationthe precipitated white phosphonium salt was collected by filtration
  3. washwashed several times with cold benzene
  4. customdried at 80° C. under high vacuum

출처 및 근거

ORD 기록
ord-77bac11b374d4b569275e985baa2db7f
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04061656

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