Pyrrolidine → Methanone, [3-nitro-4-(1-pyrrolidinyl)phenyl]phenyl-

반응식

[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1Cl)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])([O-:3])=[O:2].[NH:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1[N:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])([O-:3])=[O:2]

참가 물질

반응물 2

HCID 31268Pyrrolidine

HCID 417434-Chloro-3-nitrobenzophenone

생성물 1

HCID 2899122Methanone, [3-nitro-4-(1-pyrrolidinyl)phenyl]phenyl-수율 95%

실험 절차

3Nitro-4-chloro-benzophenone is reacted with pyrrolidine as described in Examples 7 or 8 obtain 3-nitro-4-pyrrolidino-benzophenone with a yield of 95 %. The crystalline product melts at 89.5° - 90.5° C.

출처 및 근거

ORD 기록: ord-aec211d73b4443bca25fc76c32e540c9
출처 데이터셋: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04064121

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