Benzoyl Peroxide → Methyl 2-(1-bromoethyl)benzoate

HRID 461697

반응식

HRID 461697 반응식
[CH2:1]([C:3]1[CH:12]=[CH:11][CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6])[CH3:2].[Br:13]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:13][CH:1]([C:3]1[CH:12]=[CH:11][CH:10]=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6])[CH3:2]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 583295Methyl 2-ethylbenzoate

생성물 1

HCID 15870654Methyl 2-(1-bromoethyl)benzoate

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 10.7 g. (0.065 mole) of methyl 2-ethylbenzoate, 12.5 g. (0.07 mole) of N-bromosuccinimide, 50 mg. of benzoyl peroxide, and 125 ml. of carbon tetrachloride is stirred at reflux until the reaction is complete in 2 hours. The precipitated succinimide is filtered from the cooled mixture and the filtrate is evaporated to dryness under reduced pressure leaving methyl 2-(1-bromoethyl)benzoate as the residual yellow oil in quantitative yield.

후처리

  1. additionA mixture of 10.7 g
  2. temperatureat reflux until the reaction
  3. filtrationThe precipitated succinimide is filtered from the cooled mixture
  4. customthe filtrate is evaporated to dryness under reduced pressure

출처 및 근거

ORD 기록
ord-9f80e3ccfa154d83ac3dbd8a07af416a
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04064139

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