Hydrochloric Acid → HCID 20559954, 화합물

HRID 461893노트

반응식

HRID 461893 반응식
[ClH:1].[NH2:2][C:3]1[CH:23]=[CH:22][CH:21]=[CH:20][C:4]=1[CH2:5][CH2:6][C:7]1[CH:19]=[CH:18][C:10]([C:11]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])=[O:12])=[CH:9][N:8]=1>C(O)C>[ClH:1].[ClH:1].[NH2:2][C:3]1[CH:23]=[CH:22][CH:21]=[CH:20][C:4]=1[CH2:5][CH2:6][C:7]1[CH:19]=[CH:18][C:10]([C:11]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])=[O:12])=[CH:9][N:8]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 205599556-[2-(2-Aminophenyl)ethyl]-N,N-diethylpyridine-3-carboxamide

생성물 1

HCID 20559954HCID 20559954, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

N,N-diethyl-6-(o-nitrostyryl)nicotinamide (16.3 g., 0.05 mole) reduced in 150 ml. of ethanol employing 0.1 g. of 10% palladium on carbon catalyst according to the procedure described in Example 2 (a) for 2(o-aminophenethyl)pyridine provides 6-(o-aminophenethyl)-N,N-diethylnicotinamide base. Addition of ethanolic hydrogen chloride to the nicotinamide base in ethanol provides 6-(o-aminophenethyl)-N,N-diethylnicotinamide dihydrochloride, m.p. 224°-226° C. (corr.).

출처 및 근거

ORD 기록
ord-e82686b7653b4e1cadf38f457e4f9f9a
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04064254

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