Thiophenol → [(3-Chloro-2-methylpropyl)sulfanyl]benzene
반응식
[C:1]1([SH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:9][CH:10]([CH3:13])[CH2:11][Cl:12].[OH-].[Na+]>C(O)C>[C:1]1([S:7][CH2:9][CH:10]([CH3:13])[CH2:11][Cl:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
5
반응 조건
- 온도
- 40 °C
실험 절차
A mixture of 22 g (0.2 mol) of thiophenol and 37.7 g (0.22 mol) of 3-bromo-1-chloro-2-methylpropane in 200 ml of ethanol is stirred at 40° C and 40 ml (0.2 mol) of 5N sodium hydroxide solution is added dropwise. The mixture is stirred for a further 2 hours at 40° C and evaporated to dryness in vacuo, the residue is extracted with methylene chloride and the extract is washed with water, dried and evaporated in vacuo. 39 g (97%) of a yellow oil are obtained.
후처리
- stirringThe mixture is stirred for a further 2 hours at 40° C
- customevaporated to dryness in vacuo
- extractionthe residue is extracted with methylene chloride
- washthe extract is washed with water
- customdried
- customevaporated in vacuo
출처 및 근거
- ORD 기록
- ord-c3e0945c54d74585a2e00cf4e7e1d543
- 출처 데이터셋
- uspto-grants-1977_12
- 특허 번호
- US04065584
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