Chlorine → Pyridine, 2,3,4,5-tetrachloro-6-(trichloromethyl)-

반응식

[Cl:1]Cl.[Cl:3][C:4]1[C:5]([C:12]([Cl:15])([Cl:14])[Cl:13])=[N:6][CH:7]=[C:8]([Cl:11])[C:9]=1[Cl:10]>>[Cl:3][C:4]1[C:5]([C:12]([Cl:15])([Cl:13])[Cl:14])=[N:6][C:7]([Cl:1])=[C:8]([Cl:11])[C:9]=1[Cl:10]

참가 물질

반응물 2

HCID 24526Chlorine

HCID 70990Pyridine, 3,4,5-trichloro-2-(trichloromethyl)-

생성물 1

HCID 70811Pyridine, 2,3,4,5-tetrachloro-6-(trichloromethyl)-수율 65%

실험 절차

Summarizing Example 1, starting with fifty grams of a mixture rich in 3,4,5-trichloro-2-trichloromethyl pyridine, the analysis of which is set forth in Table One, and which contained 3% by weight ferric chloride, its chlorination with 70 grams per hour of chlorine, sparged into a 250 ml glass reactor at 200° C. for 5 hours, resulted in a product the analysis of which is set forth in Table One. As will be noted, a molar yield in excess of 65% of 3,4,5,6-tetrachloro-2-trichloromethyl pyridine based on 3,4,5-trichloro-2-trichloromethyl pyridine conversion was obtained.

후처리

customsparged into a 250 ml glass reactor at 200° C. for 5 hours
customresulted in a product the analysis of which

출처 및 근거

ORD 기록: ord-15312b5ae56c4930b6453021c4f264c6
출처 데이터셋: uspto-grants-1985_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04517369

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