Dimethyl Sulfate → Ethyl 2-methoxyimino-3,3-ethylenedioxy-4-chlorobutyrate
반응식
[OH:1][N:2]=[C:3]([C:9]1([O:15][CH2:14][CH2:13][O:12]1)[CH2:10][Cl:11])[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:16](=O)([O-])[O-].[K+].[K+].S(OC)(OC)(=O)=O>CC(C)=O>[CH3:16][O:1][N:2]=[C:3]([C:9]1([O:12][CH2:13][CH2:14][O:15]1)[CH2:10][Cl:11])[C:4]([O:6][CH2:7][CH3:8])=[O:5]참가 물질
5
실험 절차
To a solution of ethyl 2-hydroxyimino-3,3-ethylenedioxy-4-chlorobutyrate (syn isomer, 0.5 g) in dried acetone (5 ml) was added potassium carbonate (0.29 g), and then dimethyl sulfate (0.265 g) was added dropwise thereto at ambient temperature with stirring. The mixture was stirred for 7 hours at ambient temperature and then filtered. The filtrate was evaporated to give ethyl 2-methoxyimino-3,3-ethylenedioxy-4-chlorobutyrate (syn isomer).
후처리
- stirringThe mixture was stirred for 7 hours at ambient temperature
- filtrationfiltered
- customThe filtrate was evaporated
출처 및 근거
- ORD 기록
- ord-9d05b9435aa442ce844054a7cee97580
- 출처 데이터셋
- uspto-grants-1985_05
- 특허 번호
- US04518774
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