4-Chloro-1,2-dinitrobenzene → ethyl P-methyl-2-nitro-5-chlorophenylphosphinate

HRID 463553

반응식

HRID 463553 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([N+]([O-])=O)[CH:3]=1.[CH3:14][P:15]([O:19]CC)[O:16][CH2:17][CH3:18]>C(#N)C>[CH3:14][P:15]([C:4]1[CH:3]=[C:2]([Cl:1])[CH:7]=[CH:6][C:5]=1[N+:8]([O-:10])=[O:9])(=[O:19])[O:16][CH2:17][CH3:18]

참가 물질

4

반응물 2

HCID 330974-Chloro-1,2-dinitrobenzeneHCID 85063Diethyl methylphosphonite

생성물 1

HCID 53860251ethyl P-methyl-2-nitro-5-chlorophenylphosphinate

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A mixture of 4-chloro-1,2-dinitrobenzene (3.31 mmol) and diethyl methylphosphonite (5.30 mmol) in 3 ml of acetonitrile is stirred at RT overnight. The mixture is then concentrated and the residue is purified by preparative TLC to yield ethyl P-methyl-2-nitro-5-chlorophenylphosphinate.

후처리

  1. concentrationThe mixture is then concentrated
  2. customthe residue is purified by preparative TLC

출처 및 근거

ORD 기록
ord-d946924498814018b352a39df226c1bf
출처 데이터셋
uspto-grants-1985_05
특허 번호
US04520197

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