4-Chlorobutanoic acid → Gamma-Butyrolactone

반응식

Cl[CH2:2][CH2:3][CH2:4][C:5]([OH:7])=[O:6].[OH-].[K+]>>[CH:4]1([C:5]([OH:7])=[O:6])[CH2:2][CH2:3]1.[C:5]1(=[O:7])[O:6][CH2:2][CH2:3][CH2:4]1

참가 물질

반응물 2

HCID 123004-Chlorobutanoic acid

HCID 14797Potassium Hydroxide

생성물 2

HCID 7302Gamma-Butyrolactone

HCID 15655Cyclopropanecarboxylic acid

실험 절차

It is known to condense the ethyl ester of 4-chlorobutyric acid with aqueous potassium hydroxide on pumice. There is obtained thereby in moderate yield the ethyl ester of cyclopropane carboxylic acid besides the free acid and γ-butyrolactone (Rambaud, BL. [5] (1938), pages 1552, 1564).