Chloroacetonitrile → HCID 20225324, 화합물

HRID 463674

반응식

HRID 463674 반응식
[CH2:1]([NH:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH3:2].Cl[CH2:12][C:13]#[N:14].C(=O)([O-])[O-].[Na+].[Na+]>C1(C)C=CC=CC=1>[CH2:1]([N:3]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH2:12][C:13]#[N:14])[CH3:2]

참가 물질

5

반응물 3

HCID 7856ChloroacetonitrileHCID 10340Sodium CarbonateHCID 480381-Heptanamine, N-ethyl-

생성물 1

HCID 20225324HCID 20225324, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
125 °C

실험 절차

Combine 7.95 g (0.055 moles) ethyl(heptyl)amine, 3.5 ml (0.055 moles) chloroacetonitrile, 5.8 g (0.055 moles) sodium carbonate and 25 ml toluene in a sealed pressure tube. Heat to 125° C. for 18 hrs. Follow the progress of the reaction by thin layer chromatography on silica gel (CH3CN+MeOH+NH4OH, 85+10+5). At the completion of the reaction, filter the reaction mixture and evaporate the solvents to provide the title compound.

후처리

  1. customthe progress of the reaction by thin layer chromatography on silica gel (CH3CN+MeOH+NH4OH, 85+10+5)
  2. customAt the completion of the reaction
  3. filtrationfilter the reaction mixture
  4. customevaporate the solvents

출처 및 근거

ORD 기록
ord-848d384f4a9e4071b0ce402d368bbeaf
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04544654

연결된 노트

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