[6-(Hydroxymethyl)pyridin-3-yl]methanol → 5-(Hydroxymethyl)pyridine-2-carboxaldehyde

HRID 464080

반응식

HRID 464080 반응식
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][OH:10])=[CH:5][N:4]=1>[O-2].[O-2].[Mn+4].C(Cl)(Cl)Cl>[CH:2]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][OH:10])=[CH:5][N:4]=1)=[O:1]

참가 물질

4

반응물 1

HCID 820251[6-(Hydroxymethyl)pyridin-3-yl]methanol

생성물 1

HCID 135185625-(Hydroxymethyl)pyridine-2-carboxaldehyde

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6212Chloroform용매

실험 절차

2,5-Di(hydroxymethyl)pyridine (10 g.) in 300 ml. of hot chloroform is treated with 100 g of manganese dioxide. After 1/2 hour of stirring, the mixture is filtered and the filtrate is evaporated to dryness to give 2-formyl-5-hydroxymethylpyridine.

후처리

  1. filtrationthe mixture is filtered
  2. customthe filtrate is evaporated to dryness

출처 및 근거

ORD 기록
ord-bd310b86aab94d3a98f09655062f091e
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04546106

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