Methanol → 4-Methoxycinnamate methyl ester

HRID 464736

반응식

HRID 464736 반응식
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1.S(=O)(=O)(O)O.[CH3:19]O>>[CH3:19][O:10][C:9](=[O:11])[CH:8]=[CH:7][C:6]1[CH:12]=[CH:13][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

참가 물질

4

반응물 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 132454-Methoxy cinnamic acid

생성물 1

HCID 928414-Methoxycinnamate methyl ester

실험 절차

A suspension of 300 g of 4-methoxycinnamic acid (J. Chem. Soc., Chem. Comm., 355, (1978)) and 25 ml of concentrated sulfuric acid in 1.7 liters of methanol is heated to reflux for 96 hours. The solution is concentrated, cooled, and filtered to give as a white solid, 4-methoxycinnamic acid methyl ester, mp 85°-86° C.

후처리

  1. temperatureis heated
  2. temperatureto reflux for 96 hours
  3. concentrationThe solution is concentrated
  4. temperaturecooled
  5. filtrationfiltered

출처 및 근거

ORD 기록
ord-cde8d7e643394330bc4208001dec3e3b
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04548947

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