2,3-Dihydro-2,4-dimethyl-7-nitrobenzofuran → HCID 13575669, 화합물

HRID 465021노트

반응식

HRID 465021 반응식
[CH3:1][CH:2]1[CH2:6][C:5]2[C:7]([CH3:14])=[CH:8][CH:9]=[C:10]([N+:11]([O-])=O)[C:4]=2[O:3]1.[H][H]>[Ni].O1CCCC1>[NH2:11][C:10]1[C:4]2[O:3][CH:2]([CH3:1])[CH2:6][C:5]=2[C:7]([CH3:14])=[CH:8][CH:9]=1

참가 물질

5

반응물 2

HCID 135756682,3-Dihydro-2,4-dimethyl-7-nitrobenzofuranHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 13575669HCID 13575669, 화합물

시약·촉매·용매 2

HCID 935Nickel촉매HCID 8028Tetrahydrofuran용매

실험 절차

A mixture of 24.3 g of 1C, 200 ml of tetrahydrofuran (THF) and 2 g of activated Raney nickel catalyst was treated with hydrogen (40 psig) in a Parr shaker three hours, then filtered. The solvent was evaporated from the filtrate to give 7-amino-2,3-dihydro-2,4-dimethylbenzofuran (1D), as an amber syrup.

후처리

  1. filtrationfiltered
  2. customThe solvent was evaporated from the filtrate

출처 및 근거

ORD 기록
ord-d11b2d305be64229a697beedc72a21a3
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04550121

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