Acetic Anhydride → HCID 9990006, 화합물

HRID 465930노트

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HRID 465930 반응식
[OH:1][CH2:2][C:3]([CH3:9])([CH3:8])[CH2:4][S:5][C:6]#[N:7].[C:10](OC(=O)C)(=[O:12])[CH3:11]>N1C=CC=CC=1>[C:10]([O:1][CH2:2][C:3]([CH3:9])([CH3:8])[CH2:4][S:5][C:6]#[N:7])(=[O:12])[CH3:11]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 104644533-Hydroxy-2,2-dimethyl-1-propylthiocyanate

생성물 1

HCID 9990006HCID 9990006, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A mixture of 58.7 g of 3-hydroxy-2,2-dimethyl-1-propylthiocyanate, 400 ml of acetic anhydride and 400 ml of pyridine was stirred for 16 hours at room temperature. The reaction solution was concentrated under reduced pressure. The residue was dissolved in 500 ml of diethyl ether. The solution was washed in turn with 1N-hydrochloric acid, water, aqueous sodium hydrogen carbonate solution and water, and dried over anhydrous magnesium sulfate. After removing the solvent, the residue was purified by distillation under reduced pressure, thereby affording 53.2 g of 3-acetoxy-2,2-dimethyl-1-propylthiocyanate.

후처리

  1. concentrationThe reaction solution was concentrated under reduced pressure
  2. dissolutionThe residue was dissolved in 500 ml of diethyl ether
  3. washThe solution was washed in turn with 1N-hydrochloric acid, water, aqueous sodium hydrogen carbonate solution and water
  4. dry with materialdried over anhydrous magnesium sulfate
  5. customAfter removing the solvent
  6. distillationthe residue was purified by distillation under reduced pressure

출처 및 근거

ORD 기록
ord-c00c62eaaf3346d88d3dde7544cda494
출처 데이터셋
uspto-grants-1992_10
특허 번호
US05155108

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