Benzoyl chloride → HCID 178510098, 화합물

HRID 466160노트

반응식

HRID 466160 반응식
C(N(CC)CC)C.[C:8](Cl)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[C:17]([C:19]1[C:20]([OH:26])=[N:21][C:22]([OH:25])=[CH:23][CH:24]=1)#[N:18]>CN(C)C(=O)C>[C:8]([O:25][C:22]1[N:21]=[C:20]([OH:26])[C:19]([C:17]#[N:18])=[CH:24][CH:23]=1)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

참가 물질

5

반응물 3

HCID 7412Benzoyl chloride2회HCID 8471Triethylamine2회HCID 178510101HCID 178510101, 화합물

생성물 1

HCID 178510098HCID 178510098, 화합물수율 60%

시약·촉매·용매 1

HCID 31374Dimethylacetamide용매

실험 절차

A 0.51 ml quantity of triethylamine and 0.43 ml of benzoyl chloride were added to a solution of 1.00 g of 3-cyano-2,6-dihydroxypyridine in 40 ml of N,N-dimethylacetamide. The mixture was stirred at room temperature for 15 minutes. To the reaction mixture were added 0.51 ml of triethylamine and 0.43 ml of benzoyl chloride, and the mixture was stirred at room temperature for 15 minutes. The reaction mixture was filtered and the filtrate was concentrated under a reduced pressure. The concentrate was washed with chloroform and with water, giving 1.06 g of the title compound in a yield of 60%.

후처리

  1. stirringthe mixture was stirred at room temperature for 15 minutes
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under a reduced pressure
  4. washThe concentrate was washed with chloroform and with water

출처 및 근거

ORD 기록
ord-4cdb991e889246a897f32b38fa11cba4
출처 데이터셋
uspto-grants-1992_10
특허 번호
US05155113

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