Hydrochloric Acid → HCID 11019906, 화합물

HRID 46633노트

반응식

HRID 46633 반응식
[ClH:1].[Cl:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[CH2:7][CH2:6]2.ClCl>C(O)(=O)C>[Cl:1][CH:7]1[CH2:6][C:5]2[C:9](=[CH:10][CH:11]=[C:3]([Cl:2])[CH:4]=2)[C:8]1=[O:12]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 24526ChlorineHCID 1425995-Chloro-1-indanone

생성물 1

HCID 11019906HCID 11019906, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

Hydrogen chloride gas is passed into a solution of 10.11 g (60 mmoles) of 5-chloro-1-indanone in 50 ml of glacial acetic acid at 10°-15° C. for 30 minutes. 4.25 g (60 mmoles) of condensed chlorine are then allowed to flow slowly into the solution at 10° C. and the mixture is allowed to come gradually to room temperature and is subsequently stirred for 3 hours. After standing overnight, the solution is poured onto ice, the oil which separates out is extracted with acetic acid ethyl ester and the solvent is distilled off under reduced pressure. The oil which remains crystallizes on standing. The product can be recrystallized from petroleum ether and then melts at 63°-66° C.

후처리

  1. customto flow slowly into the solution at 10° C.
  2. customto come gradually to room temperature
  3. waitAfter standing overnight
  4. additionthe solution is poured onto ice
  5. extractionthe oil which separates out is extracted with acetic acid ethyl ester
  6. distillationthe solvent is distilled off under reduced pressure
  7. customThe oil which remains crystallizes on standing
  8. customThe product can be recrystallized from petroleum ether

출처 및 근거

ORD 기록
ord-bed636328b5147e69634a4632a778cba
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04174397

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