Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Alendronic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Tetramethyl phthalimido-1-hydroxybutylidene-bisphosphonate | HCID 9845824 | — |
| 생성물 | Alendronic Acid | HCID 2088 | — |
반응 단계
contacting tetramethyl phthalimido-1-hydroxybutylidene-bisphosphonate from Step (b) with aqueous hydrochloric acid at a temperature in the range of 80° C. to reflux to form 4-amino-1-hydroxybutylidene-bisphosphonic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05159108 |
| 출처 데이터셋 | uspto-grants-1992_10 |
| ORD ID | ord-79a5b90cb2d34472b21ab1259fb3015e |
| 출처 메모 | uspto-grants-1992_10 |