Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(5-chlorothiophen-2-yl)acetic Acid → N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(5-chloro-2-thienyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(5-chlorothiophen-2-yl)acetic Acid | HCID 4426716 | — |
| 반응물 | 2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-one | HCID 67161367 | — |
| 생성물 | N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(5-chloro-2-thienyl)acetamide | HCID 53238659 | — |
반응 단계
The product of Example 86A and 2-(5-chlorothiophen-2-yl)acetic acid were treated using a method similar to that described in Example 5 to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.77-11.81 (bs, 1H), 8.39-8.42 (m, 1H), 7.84-8.05 (m, 2H), 7.70-7.76 (m, 1H), 7.56-7.68 (m, 4H), 6.99 (d, J=3.8 Hz, 1H), 6.92 (d, J=3.8 Hz, 1H), 3.91-3.92 (bs, 2H); MS (ESI+) M/Z 430 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08629143B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-35fb7061da3e47c6b43a99cb207d06ed |
| 출처 메모 | uspto-grants-2014_01 |