Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Iodosuccinimide → 5-Iodo-6-(trifluoromethyl)pyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Iodosuccinimide | HCID 120273 | — |
| 반응물 | 2-Amino-6-(trifluoromethyl)pyridine | HCID 821024 | — |
| 생성물 | 5-Iodo-6-(trifluoromethyl)pyridin-2-amine | HCID 58073065 | — |
반응 단계
The title compound is synthesized according to general procedure GP1 starting from 4.8 g (30 mmol) 6-trifluoromethyl-pyridin-2-ylamine and 6.7 g (30 mmol) NIS. Yield after precipitation from the reaction mixture and isolation of additional product from the mother liquid by chromatography in silica gel: 5.73 g (67%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08633183B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-e63083d2adb44062b01f7509973f862e |
| 출처 메모 | uspto-grants-2014_01 |