Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → N,N,N-trimethyl-o-nitrophenylmethanaminium iodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | N,N-dimethyl-2-nitrobenzylamine | HCID 420851 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N,N,N-trimethyl-o-nitrophenylmethanaminium iodide | HCID 86676882 | 167.6% |
반응 단계
The mixture of 57b (0.18 g, 0.5 mmol) and iodomethane (0.71 g, 5 mmol) in anhydrous CH2Cl2 (5 mL) was stirred for 12 h at r. t., then added additional iodomethane (0.71 g, 5 mmol) and continuously stirred for 12 h. After evaporation, the residue was dispensed with CH2Cl2 and filtered to give 58b (0.27 g, 84%) as yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08637490B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-248a1c7ada74457faec3cfb183cb3ff4 |
| 출처 메모 | uspto-grants-2014_01 |