反应详情

The mixture of 57b (0.18 g, 0.5 mmol) and iodomethane (0.71 g, 5 mmol) in anhydrous CH2Cl2 (5 mL) was stirred for 12 h at r. t., then added additional iodomethane (0.71 g, 5 mmol) and continuously stirred for 12 h. After evaporation, the residue was dispensed with CH2Cl2 and filtered to give 58b (0.27 g, 84%) as yellow solid.

1. stirringcontinuously stirred for 12 h
2. customAfter evaporation
3. filtrationfiltered