Hydrochloric Acid → 4-(Methylsulfanyl)piperidine hydrochloride

HRID 473803노트

반응식

HRID 473803 반응식
[CH3:1][S:2][CH:3]1[CH2:8][CH2:7][N:6](C(OC(C)(C)C)=O)[CH2:5][CH2:4]1.[ClH:16]>CO.O1CCOCC1>[ClH:16].[CH3:1][S:2][CH:3]1[CH2:8][CH2:7][NH:6][CH2:5][CH2:4]1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 11053478Tert-butyl 4-(methylthio)piperidine-1-carboxylate

생성물 1

HCID 509989504-(Methylsulfanyl)piperidine hydrochloride

시약·촉매·용매 2

HCID 887Methanol용매HCID 312751,4-Dioxane용매

실험 절차

A solution of tert-butyl 4-(methylthio)piperidine-1-carboxylate (63 mg, 0.27 mmol) in methanol (1 mL) and 4 N hydrogen chloride in dioxane (4 mL) was refluxed for 2 min and then concentrated and dried to provide 4-(methylthio)piperidine hydrochloride as a colorless oil.

후처리

  1. concentrationconcentrated
  2. customdried

출처 및 근거

ORD 기록
ord-bf18d89f947e418da75f772f78ba9115
출처 데이터셋
uspto-grants-2014_01
특허 번호
US08637499B2

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