Diisopropylethylamine → 2-methylpropyl 6-(4-{[2-(3-fluorophenyl)-4-oxopiperidin-1-yl]carbonyl}-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)-1H-imidazo[4,5-b]pyridine-1-carboxylate

반응식

FC(F)(F)C(O)=O.[O:8]1[C:14]2[CH:15]=[CH:16][C:17]([C:19]3[CH:20]=[C:21]4[N:27]([C:28]([O:30][CH2:31][CH:32]([CH3:34])[CH3:33])=[O:29])[CH:26]=[N:25][C:22]4=[N:23][CH:24]=3)=[CH:18][C:13]=2[CH2:12][NH:11][CH2:10][CH2:9]1.[F:35][C:36]1[CH:37]=[C:38]([CH:42]2[CH2:47][C:46](=[O:48])[CH2:45][CH2:44][N:43]2[C:49](Cl)=[O:50])[CH:39]=[CH:40][CH:41]=1.C(N(C(C)C)CC)(C)C>CN(C)C=O.C(OCC)(=O)C>[F:35][C:36]1[CH:37]=[C:38]([CH:42]2[CH2:47][C:46](=[O:48])[CH2:45][CH2:44][N:43]2[C:49]([N:11]2[CH2:12][C:13]3[CH:18]=[C:17]([C:19]4[CH:20]=[C:21]5[N:27]([C:28]([O:30][CH2:31][CH:32]([CH3:34])[CH3:33])=[O:29])[CH:26]=[N:25][C:22]5=[N:23][CH:24]=4)[CH:16]=[CH:15][C:14]=3[O:8][CH2:9][CH2:10]2)=[O:50])[CH:39]=[CH:40][CH:41]=1