Benzylamine → Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

HRID 476853노트

반응식

HRID 476853 반응식
CO[C:3](=[O:12])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1.[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([NH:20][C:3](=[O:12])[CH2:4][C:5]1[CH:6]=[CH:7][C:8]([OH:11])=[CH:9][CH:10]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 7504BenzylamineHCID 518900Benzeneacetic acid, 4-hydroxy-, methyl ester

생성물 1

HCID 8376026Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

실험 절차

A mixture of 80 g of 4-hydroxyphenylacetic acid methyl ester and 51.6 g of benzylamine is brought to 180° C. for 8 hours. The mixture is allowed to return to room temperature and the crystals are filtered off and washed with ethanol and then ethyl ether.

후처리

  1. customto return to room temperature
  2. filtrationthe crystals are filtered off
  3. washwashed with ethanol

출처 및 근거

ORD 기록
ord-467e9f33b6914da9b3e0388437aff99c
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886799

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