Ammonia → 2-Amino-1-phenoxy-propene

HRID 476874

반응식

HRID 476874 반응식
[O:1]([CH2:8][C:9](=O)[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:12].C1(C)C=CC(S(O)(=O)=O)=CC=1>O1CCCC1>[NH2:12][C:9]([CH3:10])=[CH:8][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 222AmmoniaHCID 6101p-Toluenesulfonic acidHCID 693131-Phenoxy-2-propanone

생성물 1

HCID 700488602-Amino-1-phenoxy-propene

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

0.2 mol of phenoxyacetone in 200 ml of tetrahydrofuran is saturated at reflux temperature with ammonia gas with the addition of 0.2 g of p-toluene sulphonic acid. The mixture is allowed to stand at room temperature for 24 hours and the solvent is then removed by evaporation in vacuo. The evaporation residue is employed crude in the reaction of Example 5B.

후처리

  1. customthe solvent is then removed by evaporation in vacuo
  2. customin the reaction of Example 5B

출처 및 근거

ORD 기록
ord-f9508f221bf3480cacb1d5f539bc49be
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886804

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