Sulfuryl chloride → HCID 14698771, 화합물

HRID 476920노트

반응식

HRID 476920 반응식
[CH2:1]([N:8]1[CH2:12][CH:11]([CH2:13]O)[O:10][C:9]1=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:19])(=O)=O>C(Cl)(Cl)Cl>[CH2:1]([N:8]1[CH2:12][CH:11]([CH2:13][Cl:19])[O:10][C:9]1=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24648Sulfuryl chlorideHCID 27937983-Benzyl-5-(hydroxymethyl)-1,3-oxazolidin-2-one

생성물 1

HCID 14698771HCID 14698771, 화합물수율 81%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

A solution of 20 g (0.1 mole) of 3-benzyl-5-hydroxymethyl-2-oxazolidinone and 24 g (0.2 mole) of sulfonyl chloride in chloroform was refluxed for 3 hr. The reaction mixture was dried over anhydrous sodium sulfate, concentrated and subjected to distillation to give 18.2 g (81%) liquid, b.p. 176°-178° C. at 0.1 mm.

후처리

  1. dry with materialThe reaction mixture was dried over anhydrous sodium sulfate
  2. concentrationconcentrated
  3. distillationsubjected to distillation

출처 및 근거

ORD 기록
ord-82f85d06cbf148ff8835d9cb30cd827d
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886794

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