Ethyl chloroacetate → 2-(2-Methyl-thiazol-4-yl)morpholin-5-one
반응식
[OH:1][CH:2]([C:5]1[N:6]=[C:7]([CH3:10])[S:8][CH:9]=1)[CH2:3][NH2:4].Cl[CH2:12][C:13](OCC)=[O:14]>C(OCC)(=O)C.CO>[CH3:10][C:7]1[S:8][CH:9]=[C:5]([CH:2]2[O:1][CH2:12][C:13](=[O:14])[NH:4][CH2:3]2)[N:6]=1참가 물질
4
실험 절차
Prepared analogously to Example S by reaction of 2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine with ethyl chloroacetate and purification on a silica gel column using ethyl acetate/methanol=19:1 as eluant.
출처 및 근거
- ORD 기록
- ord-971bae9e41fc4fdeac6716b44c2da519
- 출처 데이터셋
- uspto-grants-1989_12
- 특허 번호
- US04886814
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