Sodium Hydroxide → HCID 14076219, 화합물

HRID 477095노트

반응식

HRID 477095 반응식
[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([O:3]CC)=[O:2].[OH-].[Na+]>>[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([OH:3])=[O:2]

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 14076218HCID 14076218, 화합물

생성물 1

HCID 14076219HCID 14076219, 화합물

실험 절차

Prepared analogously to Example 2 by reaction of N-[2-(4-carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-acetylamino-4-methyl-thiazol-5-yl)ethanamine with 1N sodium hydroxide solution. After neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness, and the residue is recrystallised from 10 ml of water.

후처리

  1. customAfter neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness
  2. customthe residue is recrystallised from 10 ml of water

출처 및 근거

ORD 기록
ord-07ef8ec0d4e54431a537e639260d3a0a
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886814

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