Sodium Hydroxide → disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate

HRID 477203노트

반응식

HRID 477203 반응식
[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([NH:9][CH:10]([C:16]([O:18]CC)=[O:17])[C:11]([O:13]CC)=[O:12])=[O:8])=[O:4].[OH-].[Na+:22]>>[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([NH:9][CH:10]([C:16]([O-:18])=[O:17])[C:11]([O-:13])=[O:12])=[O:8])=[O:4].[Na+:22].[Na+:22]

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 15053734Diethyl 2-[[N-(chloroacetyl)glycyl]amino]malonate

생성물 1

HCID 19837444disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate

실험 절차

Diethyl 2-[[N-(chloroacetyl)glycyl]amino]malonate (0.68 g) is added to 1N aqueous sodium hydroxide (4.7 ml), and the mixture is reacted at room temperature for 10 hours, and the reaction mixture is concentrated. The residue is washed with methanol to give disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate (0.65 g).

후처리

  1. customthe mixture is reacted at room temperature for 10 hours
  2. concentrationthe reaction mixture is concentrated
  3. washThe residue is washed with methanol

출처 및 근거

ORD 기록
ord-952031986fac4984b79482a3558ef6ef
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886894

반응 노트

불러오는 중…