Pyrrolidine → 2-(Pyrrolidin-1-ylmethyl)morpholine

반응식

Cl[CH2:2][CH:3]1[O:8][CH2:7][CH2:6][N:5](CC2C=CC=CC=2)[CH2:4]1.[NH:16]1[CH2:20][CH2:19][CH2:18][CH2:17]1>>[N:16]1([CH2:2][CH:3]2[O:8][CH2:7][CH2:6][NH:5][CH2:4]2)[CH2:20][CH2:19][CH2:18][CH2:17]1

참가 물질

반응물 2

HCID 31268Pyrrolidine

HCID 28015624-Benzyl-2-(chloromethyl)morpholine

생성물 1

HCID 146275022-(Pyrrolidin-1-ylmethyl)morpholine

실험 절차

By the use of 2-chloromethyl-4-benzylmorpholine and pyrrolidine, the reaction is similarly carried out as Reference example 2 to give 2-(1-pyrrolidinylmethyl)morpholine.

출처 및 근거

ORD 기록: ord-8e76f4b5c2fa44ed8f24aaf89895496a
출처 데이터셋: uspto-grants-1989_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04889857

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