Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole → 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole | HCID 18771539 | — |
| 반응물 | n-Hydroxysuccinimide biotin | HCID 86743017 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole | HCID 131720117 | — |
반응 단계
To a solution containing 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole (1 equivalent) in DMF was added N-hydroxysuccinimide biotin (1.2 eq). Follwing normal workup and chromatography the title compound was obtained: CIMS (NH3, m/z): 523 (M++H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06645989B2 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-f338e18b179a493db67ab99d6cbda2f9 |
| 출처 메모 | uspto-grants-2003_11 |