Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Ethyl 6-chloropicolinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 6-Chloropicolinic acid | HCID 20812 | — |
| 생성물 | Ethyl 6-chloropicolinate | HCID 11063114 | — |
반응 단계
14.1 g (0.0895 mole) of 2-chloro-6-hydroxycarbonylpyridine in 133 ml of a solution of HCl in ethanol is heated for 8 hours under reflux. The solvent is evaporated off, ethyl acetate added and the mixture washed with a solution of bicarbonate. The solvent is further evaporated and the reaction product purified by flash chromatography (cyclohexane/ethyl acetate=7/3). The required product is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06649627B1 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-862cce06f01145b7962a2921dbe2c91c |
| 출처 메모 | uspto-grants-2003_11 |