Chlorosulfonic acid → HCID 18766653, 화합물

HRID 480927노트

반응식

HRID 480927 반응식
[C:1]([C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[C:5]([O:10][CH3:11])[CH:4]=1)#[N:2].Cl[S:13]([OH:16])(=[O:15])=[O:14]>C(Cl)(Cl)Cl>[C:1]([C:3]1[CH:9]=[CH:8][C:6]([NH:7][S:13](=[O:15])(=[O:14])[OH:16])=[C:5]([O:10][CH3:11])[CH:4]=1)#[N:2]

참가 물질

4

반응물 2

HCID 24638Chlorosulfonic acidHCID 118159314-Amino-3-methoxybenzonitrile

생성물 1

HCID 18766653HCID 18766653, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

To a solution of 4-cyano-2-methoxyaniline (1 mmol) in chloroform (1 mL) at −78° C. is added chlorosulfonic acid. Upon reaction completion, the crude material is concentrated and may be purified by recrystalization to give N-(4-cyano-2-methoxyphenyl)-sulfamic acid.

후처리

  1. customUpon reaction completion
  2. concentrationthe crude material is concentrated
  3. custommay be purified by recrystalization

출처 및 근거

ORD 기록
ord-a8a0e5620d3d4631960543ac88b34b4c
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06653347B2

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