반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-])=O.I[CH2:15][CH2:16][CH3:17].[CH3:18][CH2:19][OH:20]>>[CH2:15]([N:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][CH:12]=[CH:13][C:4]=2[NH:1][C:19](=[O:20])[CH3:18])[CH2:9]1)[CH2:16][CH3:17]참가 물질
4
실험 절차
A solution of 5-nitroisoquinoline (25 g, 0.144 mol) and iodopropane (36.7 g, 0.216 mol) in 500 mL of EtOH was converted to the title compound by the procedures described in Example 1. The crude title compound was purified by chromatography (silica gel, 95:5 EtOAc:EtOH). The purified product was recrystallized from iPr2O/THF to give the title compound as a white solid (3.33 g, 18%), mp=123° C.
출처 및 근거
- ORD 기록
- ord-6b284eb5fb784751a6f68a70a1b7e4ac
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06703391B2
연결된 노트
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