Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
반응식
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=O)=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([Cl:19])=[O:16])=[CH:5][CH:4]=1참가 물질
4
실험 절차
The (7-methoxynaphth-1-yl)acetic acid obtained above is dissolved by heating in 300 ml of chloroform. The mixture is heated under reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness. An oil is obtained which crystallizes on cooling. The residue obtained is used as such in the following stage.
후처리
- dissolutionabove is dissolved
- temperatureThe mixture is heated
- temperatureunder reflux
- temperatureThe mixture is refluxed for two hours
- customevaporated to dryness
- customAn oil is obtained which
- customcrystallizes
- temperatureon cooling
- customThe residue obtained
출처 및 근거
- ORD 기록
- ord-a5644afb33d14df0ac29383062107646
- 출처 데이터셋
- uspto-grants-1993_07
- 특허 번호
- US05225442
반응 노트
불러오는 중…