2,5-Dichlorophenol → 2,5-Dichlorophenyl Dimethyloctylsilyl Ether

HRID 483867

반응식

HRID 483867 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[OH:9].N1C=CN=C1.Cl[Si:16]([CH3:26])([CH3:25])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>CN(C)C=O.[Cl-].[Na+]>[CH3:25][Si:16]([O:9][C:3]1[CH:4]=[C:5]([Cl:8])[CH:6]=[CH:7][C:2]=1[Cl:1])([CH3:26])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

참가 물질

6

반응물 3

HCID 662,5-DichlorophenolHCID 795ImidazoleHCID 87482Chlorodimethyloctylsilane

생성물 1

HCID 539888402,5-Dichlorophenyl Dimethyloctylsilyl Ether

시약·촉매·용매 2

HCID 5234Sodium Chloride용매HCID 6228Dimethylformamide용매

실험 절차

To a solution of 3.75 g (0.023 mole) 2,5-dichlorophenol in 30 ml N,N-dimethylformamide are added 5.58 g (0.082 mole) imidazole and 16.6 ml (0.070 mole) chlorodimethyloctyl silane under argon. After stirring at room temperature for two hours, the mixture is diluted with an aqueous saturated sodium chloride solution and extracted with ether. The combined organic extracts are dried and condensed. The product is purified by column chromatography.

후처리

  1. extractionextracted with ether
  2. customThe combined organic extracts are dried
  3. customcondensed
  4. customThe product is purified by column chromatography

출처 및 근거

ORD 기록
ord-3d90883c40d24a52b08099e78da52c02
출처 데이터셋
uspto-grants-1993_07
특허 번호
US05227457

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