Water → N-(2,3-Dihydro-1H-inden-2-yl)acetamide
반응식
[NH2:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1.[C:11](OC(=O)C)(=[O:13])[CH3:12].O>N1C=CC=CC=1>[C:11]([NH:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1)(=[O:13])[CH3:12]참가 물질
5
실험 절차
2-aminoindan (6.0 g, 45 mmol) was dissolved in dry pyridine (7 ml), to which acetic anhydride (4.5 ml, 47.3 mmol) was added dropwise while cooling in ice water. After the reaction mixture was returned to room temperature and stirred for 20 minutes, water was added. The precipitate that deposited was filtered to obtain 2-acetamidoindan (5.6 g, 32 mmol).
후처리
- additionwas added dropwise
- customwas returned to room temperature
- filtrationThe precipitate that deposited was filtered
출처 및 근거
- ORD 기록
- ord-98d057ea4c4f49e8bf8e66ae144e62ee
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06703421B1
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