[H-].[Na+].[NH:3]1[CH:7]=[CH:6][CH:5]=[N:4]1.[H][H].Cl[CH2:11][CH2:12][CH:13]1[CH2:19][N:18]([CH3:20])[C:17](=[S:21])[C:16]2[CH:22]=[CH:23][CH:24]=[N:25][C:15]=2[O:14]1>CN(C)C=O>[CH3:20][N:18]1[C:17](=[S:21])[C:16]2[CH:22]=[CH:23][CH:24]=[N:25][C:15]=2[O:14][CH:13]([CH2:12][CH2:11][N:3]2[CH:7]=[CH:6][CH:5]=[N:4]2)[CH2:19]1To a suspension of 2.16 g (0.054 mole) of sodium hydride in 20 ml of dimethylformamide was added dropwise a solution of 2.92 g (0.043 mole) of pyrazole in 10 ml of dimethylformamide. There was a slight exotherm at this point with some evolution of hydrogen gas. The resulting solution was then added dropwise to a solution of 10.0 g (0.039 mole) of 2-(2-chloroethyl)-2,3-dihydro-4-methylpyrido[3,2-f]-1,4-oxazepine-5(4H)-thione in 30 ml of dimethylformamide. The reaction flask was sealed and stirred overnight at room temperature.
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