Butylamine → n-Butyl-2,2,6,6-tetramethyl-4-piperidinamine

HRID 484934

반응식

HRID 484934 반응식
[CH3:1][C:2]1([CH3:11])[CH2:7][C:6](=O)[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3]1.[CH2:12]([NH2:16])[CH2:13][CH2:14][CH3:15]>CO.[Pt]=O>[CH2:12]([NH:16][CH:6]1[CH2:7][C:2]([CH3:11])([CH3:1])[NH:3][C:4]([CH3:10])([CH3:9])[CH2:5]1)[CH2:13][CH2:14][CH3:15]

참가 물질

5

반응물 2

HCID 8007ButylamineHCID 132202,2,6,6-Tetramethyl-4-piperidone

생성물 1

HCID 118285n-Butyl-2,2,6,6-tetramethyl-4-piperidinamine

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

2.0 g of platinum oxide were added to a solution of 155 g of 2,2,6,6-tetramethyl-4-piperidone and 80 g of butylamine in 300 ml of methanol. The resulting mixture was then hydrogenated under a hydrogen atmosphere in a Parr hydrogenation apparatus at room temperature for 5 hours. After completion of the reaction, the platinum catalyst was filtered off and the solvent was distilled from the filtrate under reduced pressure. The residue was purified by vacuum distillation, to give the desired product as an oil, boiling at 100°-101° C./5 mmHg (667 Pascals).

후처리

  1. customAfter completion of the reaction
  2. filtrationthe platinum catalyst was filtered off
  3. distillationthe solvent was distilled from the filtrate under reduced pressure
  4. distillationThe residue was purified by vacuum distillation

출처 및 근거

ORD 기록
ord-929b6e37381541248af7dca6487180fd
출처 데이터셋
uspto-grants-1985_08
특허 번호
US04533688

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