Sodium Azide → HCID 13338731, 화합물

HRID 485669노트

반응식

HRID 485669 반응식
Br[CH:2]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[NH:4][C:3]1=[O:15].[N-:16]=[N+:17]=[N-:18].[Na+]>CS(C)=O>[N:16]([CH:2]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]2[CH:11]=[CH:12][CH:13]=[CH:14][C:5]=2[NH:4][C:3]1=[O:15])=[N+:17]=[N-:18]

참가 물질

4

반응물 2

HCID 33557Sodium AzideHCID 13338730HCID 13338730, 화합물

생성물 1

HCID 13338731HCID 13338731, 화합물

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

A solution of 3-bromo-1,3,4,5,6,7-hexahydro-1-benzazonin-2-one (14.2 g) and sodium azide (7.1 g) in dimethylsulfoxide (400 ml) is maintained at 80° under an atmosphere of nitrogen for 3 hours. The reaction mixture is poured into ice/water (1200 ml) and the suspension is stirred for 30 minutes. The solid is filtered off, washed with water (300 ml) and dried to give 3-azido-1,3,4,5,6,7-hexahydro-1-benzazonin-2-one.

후처리

  1. filtrationThe solid is filtered off
  2. washwashed with water (300 ml)
  3. customdried

출처 및 근거

ORD 기록
ord-56d616c7e96c4ea9b840e1a5faa149f6
출처 데이터셋
uspto-grants-1985_08
특허 번호
US04537885

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