Acetic Anhydride → HCID 19095933, 화합물

HRID 486779노트

반응식

HRID 486779 반응식
[OH:1][C:2]1[C:7]2=[CH:8][C:9]3[C:14]([N:6]2[CH2:5][CH:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:3]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:13][CH:12]=[CH:11][CH:10]=3.[C:25](OC(=O)C)(=[O:27])[CH3:26]>N1C=CC=CC=1>[C:25]([O:1][C:2]1[C:7]2=[CH:8][C:9]3[C:14]([N:6]2[CH2:5][CH:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:3]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:13][CH:12]=[CH:11][CH:10]=3)(=[O:27])[CH3:26]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 54684685HCID 54684685, 화합물

생성물 1

HCID 19095933HCID 19095933, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

From a mixture of 29.3 g of diethyl 6,7-dihydro-9-hydroxypyrido[1,2-a]indole-7,8-dicarboxylate, 100 ml of pyridine and 30 ml of acetic anhydride, the solvents were removed under reduced pressure and the residue was partitioned between ethyl acetate and 2M hydrochloric acid. The organic extract was washed with saturated sodium bicarbonate solution and water, dried and evaporated to give 33 g of diethyl 9-acetoxy-6,7-dihydropyrido[1,2-a]indole-7,8-dicarboxylate.

후처리

  1. customthe solvents were removed under reduced pressure
  2. customthe residue was partitioned between ethyl acetate and 2M hydrochloric acid
  3. extractionThe organic extract
  4. washwas washed with saturated sodium bicarbonate solution and water
  5. customdried
  6. customevaporated

출처 및 근거

ORD 기록
ord-f40ad0f0844745faa02dbe3e7719ce53
출처 데이터셋
uspto-grants-1994_03
특허 번호
US05292747

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