Hydrochloric Acid → 1-Phenyl-2-chloro-2-methylpropane

HRID 488600노트

반응식

HRID 488600 반응식
[C:1]1([CH2:7][C:8](O)([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:12]>>[C:1]1([CH2:7][C:8]([Cl:12])([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 75312-Methyl-1-phenyl-2-propanol

생성물 1

HCID 2963571-Phenyl-2-chloro-2-methylpropane

실험 절차

A mixture of 5.92 g (40 mmoles) of 1-phenyl-2-hydroxy-2-methylpropane and 50 mL conc. hydrochloric acid was stirred at ice bath temperature for 1 h and at RT for 3 h. The reaction mixture was then extracted with ether. The organic layer was dried over MgSO4. Solvent removal gave 1-phenyl-2-chloro-2-methylpropane.

후처리

  1. waitat RT for 3 h
  2. extractionThe reaction mixture was then extracted with ether
  3. dry with materialThe organic layer was dried over MgSO4
  4. customSolvent removal

출처 및 근거

ORD 기록
ord-71517d87ceb4473aa3e70aa0bb52bb35
출처 데이터셋
uspto-grants-2005_12
특허 번호
US06972295B2

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