참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 4-Chloroquinoline | HCID 69140 | — |
| 반응물 | 4-Amino-2-Nitrophenol | HCID 3417419 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 2-Nitro-4-(quinolin-4-ylamino)-phenol | HCID 69018454 | — |
반응 단계
TFA (0.57 mL) was added to a suspension of 4-chloroquinoline (0.48 mg, 2.9 mmol) and 4-amino-2-nitrophenol (0.45 g, 2.9 mmol) in i-PrOH (4 mL) was added at RT. The reaction was heated to 130° C. in a sealed tube for 2 h. A solid precipitated upon cooling. The solid was filtered out and washed with i-PrOH to give 2-nitro-4-(quinolin-4-ylamino)-phenol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07531553B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_05 |
|---|
| ORD ID | ord-d147708c38884f24a17fa4db806b74d8 |
|---|
| 출처 메모 | uspto-grants-2009_05 |
|---|
