참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 4-Methoxy-4'-nitrobiphenyl | HCID 11128079 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-Hydroxy-4'-nitrobiphenyl | HCID 138078 | — |
반응 단계
4′-Methoxy-4-nitro-biphenyl (4.55 g, 19.8 mmol), prepared in the previous step, in a mixture of glacial acetic acid plus 65 mL of 48% HBr was heated at approximately 120° C. until the reaction was complete by TLC. The reaction was concentrated under reduced pressure and the residue partitioned between diethyl ether and water. The organic layer was separated, dried (Na2SO4) and the solvent removed under reduced pressure to give 4′-hydroxy-4-nitro-biphenyl.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07534894B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_05 |
|---|
| ORD ID | ord-b96104b8c75c422aacbc263d6a4065c5 |
|---|
| 출처 메모 | uspto-grants-2009_05 |
|---|
