Sodium Hydroxide → 1-(Methoxycarbonyl)cyclopropane-1-carboxylic acid

HRID 496054노트

반응식

HRID 496054 반응식
[OH-].[Na+].[C:3]1([C:10]([O-:12])=[O:11])([C:6]([O:8][CH3:9])=[O:7])[CH2:5][CH2:4]1>CO>[CH3:9][O:8][C:6]([C:3]1([C:10]([OH:12])=[O:11])[CH2:5][CH2:4]1)=[O:7]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 22325078Monomethyl cyclopropane-1,1-dicarboxylate

생성물 1

HCID 138618231-(Methoxycarbonyl)cyclopropane-1-carboxylic acid

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

1.45 liters of 1N sodium hydroxide solution are added to a solution, cooled to 5° C., of 1.45 ml of methyl 1,1-cyclopropanedicarboxylate in 2.5 liters of methanol. After stirring for 4 days at ambient temperature, the mixture is three-quarters concentrated, extracted with ether and then treated in customary manner, allowing the expected product to be isolated.

후처리

  1. concentrationconcentrated
  2. extractionextracted with ether
  3. additiontreated in customary manner
  4. customto be isolated

출처 및 근거

ORD 기록
ord-4a70eccecef643dd8b83003fe0b11ca1
출처 데이터셋
uspto-grants-2005_09
특허 번호
US06943184B2

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