Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetamidomalonic acid diethyl ester → N-acetyl-2-ethoxycarbonyl-3-(4-methoxyphenyl)proline ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetamidomalonic acid diethyl ester | HCID 14041 | — |
| 반응물 | 3-(4-Methoxyphenyl)prop-2-enal | HCID 230995 | — |
| 생성물 | N-acetyl-2-ethoxycarbonyl-3-(4-methoxyphenyl)proline ethyl ester | HCID 10021599 | 79.5% |
반응 단계
N-Acetyl-2-ethoxycarbonyl-3-(4-methoxyphenyl)proline, ethyl ester (13 g, 72%) was prepared from 4-methoxycinnamaldehyde (Lancaster, 8.1 g, 50 mmol) and diethyl acetamidomalonate (Aldrich, 9.9 g, 45 mmol) by the procedure described by Chung et al (J. Org. Chem. 1990, 55, 270).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06943180B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-29f119994b164dc189e90a8054097d9b |
| 출처 메모 | uspto-grants-2005_09 |