Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 497934생성일: 2026년 10월 25일
Diethyl (ethoxymethylene)malonate → Diethyl 2-([[3-methyl-1-(2-pyridinyl)-1H-pyrazol-5-yl]amino]methylene)malonate
https://huagongshe.com/reaction/497934
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| 반응물 | 3-Methyl-1-(pyridin-2-yl)-1H-pyrazol-5-amine | HCID 735132 | — |
| 생성물 | Diethyl 2-([[3-methyl-1-(2-pyridinyl)-1H-pyrazol-5-yl]amino]methylene)malonate | HCID 22320362 | 96% |
반응 단계
A mixture of diethyl ethoxymethylenemalonate (32.5 g, 0.15 mol) and 3-methyl-1-(2-pyridinyl)-1H-pyrazol-5-amine (23.8 g, 0.137 mol) was heated under reflux at 120° C. for 1 hour. After the mixture was allowed to cool to room temperature, the reaction solvent was evaporated under reduced pressure. The crude crystals thus obtained were filtered and washed with diethylether to give the title compound (45 g, 96% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US06949648B2 |
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| 출처 데이터셋 | uspto-grants-2005_09 |
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| ORD ID | ord-34b8fc18d8c74f8bba3d7ab89fdd719a |
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| 출처 메모 | uspto-grants-2005_09 |
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