Dimethylformamide dimethyl acetal → HCID 54124074, 화합물
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[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:15])[CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11].[CH3:16][N:17]([CH:19](OC)OC)[CH3:18]>C1(C)C=CC=CC=1>[CH2:13]([O:12][C:10](=[O:11])[C:9]([C:8](=[O:15])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])=[CH:16][N:17]([CH3:19])[CH3:18])[CH3:14]참가 물질
4
실험 절차
A mixture of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (14.29 g, 68.0 mmol) and DMF-DMA (12.15 g, 0.102 mol, 1.5 eq.) in toluene (50 mL) was refluxed for 2 hours and concentrated to give 3-dimethylamino-2-(2-fluoro-benzoyl)-acrylic acid ethyl ester as a red oil in quantitative yield.
후처리
- temperaturewas refluxed for 2 hours
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-205848d57c714bb787ac709c90f0e4d6
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07767680B2
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